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K27M-mutant histone-3 as a novel target for glioma immunotherapy

Mutation-specific vaccines have become increasingly important in glioma immunotherapy; however, shared neoepitopes are rare. For diffuse gliomas, a driver mutation in the gene for isocitrate dehydrogenase type-1 has been shown to produce an immunogenic epitope currently targeted in clinical trials....

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Ochs, Katharina, Ott, Martina, Bunse, Theresa, Sahm, Felix, Bunse, Lukas, Deumelandt, Katrin, Sonner, Jana K., Keil, Melanie, von Deimling, Andreas, Wick, Wolfgang, Platten, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543817/
https://ncbi.nlm.nih.gov/pubmed/28811969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1328340
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