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Metabolic regulation of T cell longevity and function in tumor immunotherapy

Cancer immunotherapy is an increasingly successful strategy for the treatment of patients who have advanced or conventional therapy-resistant cancers. T cells are key mediators of tumor destruction and their specificity for tumor-expressed antigens is of paramount importance, but other T cell-intrin...

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Bibliografiske detaljer
Udgivet i:Cell Metab
Main Authors: Kishton, Rigel J., Sukumar, Madhusudhanan, Restifo, Nicholas P
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543711/
https://ncbi.nlm.nih.gov/pubmed/28683298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2017.06.016
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