T Cell Transcriptomes from Paroxysmal Nocturnal Hemoglobinuria Patients Reveal Novel Signaling Pathways

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired disorder originating from hematopoietic stem cells (HSCs) and a life-threating disease characterized by intravascular hemolysis, bone marrow (BM) failure, and venous thrombosis. The etiology of PNH is a somatic mutation in the phosphatidyl...

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Publicado en:J Immunol
Autores principales: Hosokawa, Kohei, Kajigaya, Sachiko, Keyvanfar, Keyvan, Qiao, Wangmin, Xie, Yanling, Townsley, Danielle M., Feng, Xingmin, Young, Neal S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543699/
https://ncbi.nlm.nih.gov/pubmed/28630090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601299
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