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Chromosome translocations clustered 5' of the murine c-myc gene qualitatively affect promoter usage: implications for the site of normal c-myc regulation.

Five novel murine plasma cell (PC) tumors with chromosome translocations 350-500 bp 5' of the first c-myc exon are described. The t(12;15)s of TEPC 1194, ABPC 33 and TEPC 1165 position the intact c-myc locus 5' of the Cu, C gamma 2a and C alpha IgCH genes respectively. In ABPC 17, the IgH...

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Bibliografske podrobnosti
izdano v:EMBO J
Main Authors: Yang, J Q, Bauer, S R, Mushinski, J F, Marcu, K B
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1985
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC554365/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2992931/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1985.tb03800.x
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