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Zoledronate treatment has different effects in mouse strains with contrasting baseline bone mechanical phenotypes

INTRODUCTION: Bisphosphonates are highly effective in reducing fracture risk yet some individuals treated with these agents still experience fracture. The goal of this study was to test the hypothesis that genotype influences the effect of zoledronate on bone mechanical properties. METHODS: Skeletal...

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Publicat a:Osteoporos Int
Autors principals: Aref, Mohammad W., McNerny, Erin M.B., Brown, Drew, Jepsen, Karl J., Allen, Matthew R.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543625/
https://ncbi.nlm.nih.gov/pubmed/27439372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00198-016-3701-9
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