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Tanshinone IIA Protects Hippocampal Neuronal Cells from Reactive Oxygen Species Through Changes in Autophagy and Activation of Phosphatidylinositol 3-Kinase, Protein Kinas B, and Mechanistic Target of Rapamycin Pathways

BACKGROUND: Tanshinone IIA is a key active ingredient of danshen, which is derived from the dried root or rhizome of Salviae miltiorrhizae Bge. The tanshinone IIA has protective effects against the focal cerebral ischemic injury. However, the underlying mechanisms remain unclear. METHODS: An in vitr...

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Detalhes bibliográficos
Publicado no:Curr Neurovasc Res
Main Authors: Zhu, Yingchun, Tang, Qiqiang, Wang, Guoping, Han, Ruodong
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543574/
https://ncbi.nlm.nih.gov/pubmed/28260507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1567202614666170306105315
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