Overexpression of B‐cell lymphoma 6 alters gene expression profile in a myeloma cell line and is associated with decreased DNA damage response

B‐cell lymphoma 6 (BCL6) attenuates DNA damage response (DDR) through gene repression and facilitates tolerance to genomic instability during immunoglobulin affinity maturation in germinal center (GC) B cells. Although BCL6 expression is repressed through normal differentiation of GC B cells into pl...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cancer Sci
Auteurs principaux: Tahara, Kenichi, Takizawa, Makiko, Yamane, Arito, Osaki, Yohei, Ishizaki, Takuma, Mitsui, Takeki, Yokohama, Akihiko, Saitoh, Takayuki, Tsukamoto, Norifumi, Matsumoto, Morio, Murakami, Hirokazu, Nojima, Yoshihisa, Handa, Hiroshi
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2017
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543477/
https://ncbi.nlm.nih.gov/pubmed/28544233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13283
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