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Global N-glycan Site Occupancy of HIV-1 gp120 by Metabolic Engineering and High-Resolution Intact Mass Spectrometry

A vital step in HIV vaccine development strategies has been the observation that some infected individuals generate broadly neutralizing antibodies that target the glycans on the surface of HIV-1 gp120. These antibodies target glycan epitopes on viral envelope spikes and yet the positions and degree...

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Publicat a:ACS Chem Biol
Autors principals: Struwe, Weston B., Stuckmann, Alexandra, Behrens, Anna-Janina, Pagel, Kevin, Crispin, Max
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543417/
https://ncbi.nlm.nih.gov/pubmed/27984693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00854
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