Effect of carboxylesterase 1 S75N on clopidogrel therapy among acute coronary syndrome patients

Carboxylesterase 1 (CES1) hydrolyzes the prodrug clopidogrel to an inactive carboxylic acid metabolite. The effects of CES1 S75N (rs2307240,C>T) on clopidogrel response among 851 acute coronary syndrome patients who came from the north, central and south of China were studied. The occurrence rati...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Xiao, Fei-Yan, Luo, Jian-Quan, Liu, Min, Chen, Bi-Lian, Cao, Shan, Liu, Zhao-Qian, Zhou, Hong-Hao, Zhou, Gan, Zhang, Wei
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543069/
https://ncbi.nlm.nih.gov/pubmed/28775293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07736-1
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