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Bacterial deception of MAIT cells in a cloud of superantigen and cytokines

The bacterium Staphylococcus aureus is an important cause of the life-threatening condition toxic shock syndrome in humans. Bacterial toxins known as superantigens (SAgs) generate this illness by acting as broad activators of a substantial fraction of all T lymphocytes, bypassing the normally highly...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Sandberg, Johan K., Norrby-Teglund, Anna, Leeansyah, Edwin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542701/
https://ncbi.nlm.nih.gov/pubmed/28742082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2003167
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