Pathological manifestations in lymphatic filariasis correlate with lack of inhibitory properties of IgG4 antibodies on IgE-activated granulocytes

Helminth parasites are known to be efficient modulators of their host’s immune system. To guarantee their own survival, they induce alongside the classical Th2 a strong regulatory response with high levels of anti-inflammatory cytokines and elevated plasma levels of IgG4. This particular antibody wa...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Prodjinotho, Ulrich F., von Horn, Charlotte, Debrah, Alex Y., Batsa Debrah, Linda, Albers, Anna, Layland, Laura E., Hoerauf, Achim, Adjobimey, Tomabu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542694/
https://ncbi.nlm.nih.gov/pubmed/28742098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005777
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