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Refinement of immunizing antigens to produce functional blocking antibodies against the AniA nitrite reductase of Neisseria gonorrhoeae

The emergence of multi-drug resistant Neisseria gonorrhoeae has generated an urgent need for novel therapies or a vaccine to prevent gonococcal disease. In this study we investigate the potential of targeting the surface exposed nitrite reductase, AniA, to block activity by producing functional bloc...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Shewell, Lucy K., Jen, Freda E.-C, Jennings, Michael P.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542605/
https://ncbi.nlm.nih.gov/pubmed/28771632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182555
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