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Refinement of immunizing antigens to produce functional blocking antibodies against the AniA nitrite reductase of Neisseria gonorrhoeae

The emergence of multi-drug resistant Neisseria gonorrhoeae has generated an urgent need for novel therapies or a vaccine to prevent gonococcal disease. In this study we investigate the potential of targeting the surface exposed nitrite reductase, AniA, to block activity by producing functional bloc...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Shewell, Lucy K., Jen, Freda E.-C, Jennings, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542605/
https://ncbi.nlm.nih.gov/pubmed/28771632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182555
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