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An evolutionarily conserved glycine-tyrosine motif forms a folding core in outer membrane proteins

An intimate interaction between a pair of amino acids, a tyrosine and glycine on neighboring β-strands, has been previously reported to be important for the structural stability of autotransporters. Here, we show that the conservation of this interacting pair extends to nearly all major families of...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Michalik, Marcin, Orwick-Rydmark, Marcella, Habeck, Michael, Alva, Vikram, Arnold, Thomas, Linke, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542473/
https://ncbi.nlm.nih.gov/pubmed/28771529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182016
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