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EBV epigenetically suppresses the B cell-to-plasma cell differentiation pathway while establishing long-term latency
Mature human B cells infected by Epstein-Barr virus (EBV) become activated, grow, and proliferate. If the cells are infected ex vivo, they are transformed into continuously proliferating lymphoblastoid cell lines (LCLs) that carry EBV DNA as extra-chromosomal episomes, express 9 latency-associated E...
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| Publicado no: | PLoS Biol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5542390/ https://ncbi.nlm.nih.gov/pubmed/28771465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2001992 |
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