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Autophagy and mitophagy in the context of doxorubicin-induced cardiotoxicity
Doxorubicin (Dox) is a cytotoxic drug widely incorporated in various chemotherapy protocols. Severe side effects such as cardiotoxicity, however, limit Dox application. Mechanisms by which Dox promotes cardiac damage and cardiomyocyte cell death have been investigated extensively, but a definitive p...
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| Veröffentlicht in: | Oncotarget |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Impact Journals LLC
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5542301/ https://ncbi.nlm.nih.gov/pubmed/28445146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16944 |
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