Increased S100A15 expression and decreased DNA methylation of its gene promoter are involved in high metastasis potential and poor outcome of lung adenocarcinoma

PURPOSE: This study aims to determine the functional role of S100A15 and its promoter DNA methylation patterns in lung cancer progression. EXPERIMENTAL DESIGN: We analyzed 178 formalin-fixed paraffin embedded specimens from lung cancer patients, including 24 early stage and 91 advanced stage adenoca...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chen, Yung-Che, Lin, Meng-Chih, Hsiao, Chang-Chun, Zheng, Yi-Xin, Chen, Kuang-Den, Sung, Ming-Tse, Chen, Chung-Jen, Wang, Ting-Ya, Lin, Yong-Yong, Chang, Huang-Chih, Chen, Yu-Mu, Chang, Jen-Chieh
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542220/
https://ncbi.nlm.nih.gov/pubmed/28498804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17391
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