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Molecular characterization of circulating tumor cells from patients with metastatic breast cancer reflects evolutionary changes in gene expression under the pressure of systemic therapy

Resistance to systemic therapy is a major problem in metastatic breast cancer (MBC) that can be explained by initial tumor heterogeneity as well as by evolutionary changes during therapy and tumor progression. Circulating tumor cells (CTCs) detected in a liquid biopsy can be sampled and characterize...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Aaltonen, Kristina E., Novosadová, Vendula, Bendahl, Pär-Ola, Graffman, Cecilia, Larsson, Anna-Maria, Rydén, Lisa
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542207/
https://ncbi.nlm.nih.gov/pubmed/28489591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17271
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