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DNA methylation mediated silencing of microRNA-874 is a promising diagnosis and prognostic marker in breast cancer

MicroRNA-874 (miR-874) is downregulated in several human cancers and has been suggested to be a tumor suppressor gene. However, the molecular mechanism of miR-874 downregulation in breast cancer has not been well elucidated. Here we aimed to study the aberrant hyper-methylation of CpG sites with the...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Zhang, Lei, Yan, Da-Li, Yang, Fan, Wang, Dan-Dan, Chen, Xiu, Wu, Jian-Zhong, Tang, Jin-Hai, Xia, Wen-Jie
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542203/
https://ncbi.nlm.nih.gov/pubmed/28525377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17569
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