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PI3K inhibitor enhances the cytotoxic response to etoposide and cisplatin in a newly established neuroendocrine cervical carcinoma cell line

BACKGROUND: Neuroendocrine cervical carcinoma (NECC) is a rare and aggressive subtype of cervical cancer. To date, no NECC cell-based model is available, which hinders the development of new therapeutic strategies for NECC. In this study, we derived a new NECC cell line from an ex vivo biopsy and us...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lai, Zih-Yin, Yeo, Hsin-Yueh, Chen, Ya-Tse, Chang, Kuo-Ming, Chen, Tze-Chien, Chuang, Yung-Jen, Chang, Shing-Jyh
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542189/
https://ncbi.nlm.nih.gov/pubmed/28484083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17335
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