Circulating LOXL2 Levels Reflect Severity of Intestinal Fibrosis and GALT CD4(+) T Lymphocyte Depletion in Treated HIV Infection

BACKGROUND: Incomplete immune reconstitution may occur despite successful antiretroviral therapy (ART). Gut-associated lymphoid tissue (GALT) fibrosis may contribute via local CD4(+) T lymphocyte depletion, intestinal barrier disruption, microbial translocation, and immune activation. METHODS: In a...

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Detalhes bibliográficos
Publicado no:Pathog Immun
Main Authors: Seang, Sophie, Somasunderam, Anoma, Nigalye, Maitreyee, Somsouk, Ma, Schacker, Timoty W., Sanchez, Joyce L., Hunt, Peter W., Utay, Netanya S., Lake, Jordan E.
Formato: Artigo
Idioma:Inglês
Publicado em: Pathogens and Immunity 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542020/
https://ncbi.nlm.nih.gov/pubmed/28782046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20411/pai.v2i2.180
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