miR-200b inhibits proliferation and metastasis of breast cancer by targeting fucosyltransferase IV and α1,3-fucosylated glycans

Aberrant protein fucosylation is associated with cancer malignancy. Fucosyltransferase IV (FUT4) is the key enzyme catalyzing the biosynthesis of α1,3-linkage fucosylated glycans carried by glycoproteins on the cell surface, such as the tumor-associated sugar antigen Lewis Y (LeY). An abnormal incre...

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Detalles Bibliográficos
Publicado en:Oncogenesis
Main Authors: Zheng, Q, Cui, X, Zhang, D, Yang, Y, Yan, X, Liu, M, Niang, B, Aziz, F, Liu, S, Yan, Q, Liu, J
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541710/
https://ncbi.nlm.nih.gov/pubmed/28692034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2017.58
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