SRGN-TGFβ2 regulatory loop confers invasion and metastasis in triple-negative breast cancer

Patients with triple-negative breast cancers (TNBC) are at a high risk for a recurrent or metastatic disease, and the molecular mechanisms associated with this risk are unclear. Proteoglycan serglycin (SRGN) proteins are involved in tumor metastasis, but their role in TNBC has not yet been elucidate...

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Publicado en:Oncogenesis
Autores principales: Zhang, Z, Deng, Y, Zheng, G, Jia, X, Xiong, Y, Luo, K, Qiu, Q, Qiu, Ni, Yin, J, Lu, M, Liu, H, Gu, Y, He, Z
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2017
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541705/
https://ncbi.nlm.nih.gov/pubmed/28692037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2017.53
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