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Serum, like phorbol esters, rapidly activates protein kinase C in intact quiescent fibroblasts.

Addition of serum to quiescent cultures of Swiss 3T3 cells and mouse embryo fibroblasts causes a rapid increase in the phosphorylation of an 80 000 mol. wt. cellular protein (termed 80 K). The effect is dose- and time-dependent; enhancement in 80 K phosphorylation can be detected as early as 10-15 s...

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Bibliographic Details
Main Authors: Rodriguez-Pena, A, Rozengurt, E
Format: Artigo
Language:Inglês
Published: 1985
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC554153/
https://ncbi.nlm.nih.gov/pubmed/3160581
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