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CD133(+) brain tumor-initiating cells are dependent on STAT3 signaling to drive medulloblastoma recurrence
Medulloblastoma (MB), the most common malignant paediatric brain tumor, is currently treated using a combination of surgery, craniospinal radiotherapy and chemotherapy. Owing to MB stem cells (MBSCs), a subset of MB patients remains untreatable despite standard therapy. CD133 is used to identify MBS...
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Publicado no: | Oncogene |
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Main Authors: | , , , , , , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5541269/ https://ncbi.nlm.nih.gov/pubmed/27775079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.235 |
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