Preferential production of IgM-secreting hybridomas by immunization with DNA vaccines coding for Ebola virus glycoprotein: use of protein boosting for IgG-secreting hybridoma production

PURPOSE: The goal of this study was to investigate the utility of DNA vaccines encoding Ebola virus glycoprotein (GP) as a vaccine type for the production of GP-specific hybridomas and antibodies. MATERIALS AND METHODS: DNA vaccines were constructed to express Ebola virus GP. Mice were injected with...

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Detalhes bibliográficos
Publicado no:Clin Exp Vaccine Res
Main Authors: Lee, Si-Hyeong, Han, Baek-Sang, Choe, Jongseon, Sin, Jeong-Im
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Vaccine Society 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540962/
https://ncbi.nlm.nih.gov/pubmed/28775978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7774/cevr.2017.6.2.135
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