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What Are the Most Powerful Immunogen Design Vaccine Strategies?: Reverse Vaccinology 2.0 Shows Great Promise
Functional antibodies, i.e., those with antipathogen activity in in vitro assays, are generally the best correlate of vaccine protection. Mimics of natural infection, including live attenuated and killed pathogens, which induce such antibodies in vivo, have generated highly successful vaccines. Howe...
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| Publicado en: | Cold Spring Harb Perspect Biol |
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| Autor principal: | |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2017
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5540812/ https://ncbi.nlm.nih.gov/pubmed/28159875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a030262 |
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