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Elevated arginase I expression in rat aortic smooth muscle cells increases cell proliferation
Arginase, which exists as the isoforms arginase I and II, catalyzes the hydrolysis of arginine to ornithine and urea. Ornithine is the principal precursor for production of polyamines, which are required for cell proliferation. Rat aortic smooth muscle cells (RASMC) contain constitutive arginase I,...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The National Academy of Sciences
2001
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC55408/ https://ncbi.nlm.nih.gov/pubmed/11470919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.161294898 |
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