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Elevated arginase I expression in rat aortic smooth muscle cells increases cell proliferation

Arginase, which exists as the isoforms arginase I and II, catalyzes the hydrolysis of arginine to ornithine and urea. Ornithine is the principal precursor for production of polyamines, which are required for cell proliferation. Rat aortic smooth muscle cells (RASMC) contain constitutive arginase I,...

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Detalhes bibliográficos
Main Authors: Wei, Liu Hua, Wu, Guoyao, Morris, Sidney M., Ignarro, Louis J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC55408/
https://ncbi.nlm.nih.gov/pubmed/11470919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.161294898
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