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Drosophila LKB1 is required for the assembly of the polarized actin structure that allows spermatid individualization

In mammals, a testis-specific isoform of the protein kinase LKB1 is required for spermiogenesis, but its exact function and specificity are not known. Human LKB1 rescues the functions of Drosophila Lkb1 essential for viability, but these males are sterile, revealing a new function for this genes in...

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Pubblicato in:PLoS One
Autori principali: Couderc, Jean-Louis, Richard, Graziella, Vachias, Caroline, Mirouse, Vincent
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540607/
https://ncbi.nlm.nih.gov/pubmed/28767695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182279
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