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DNA mutation motifs in the genes associated with inherited diseases

Mutations in human genes can be responsible for inherited genetic disorders and cancer. Mutations can arise due to environmental factors or spontaneously. It has been shown that certain DNA sequences are more prone to mutate. These sites are termed hotspots and exhibit a higher mutation frequency th...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Růžička, Michal, Kulhánek, Petr, Radová, Lenka, Čechová, Andrea, Špačková, Naďa, Fajkusová, Lenka, Réblová, Kamila
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540541/
https://ncbi.nlm.nih.gov/pubmed/28767725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182377
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