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Serum Factors from Pseudoxanthoma Elasticum Patients Alter Elastic Fiber Formation In Vitro

Pseudoxanthoma elasticum (PXE) is a heritable disorder mainly characterized by calcified elastic fibers in cutaneous, ocular, and vascular tissues. PXE is caused by mutations in ABCC6, a gene encoding an ABC transporter predominantly expressed in liver and kidneys. The functional relationship betwee...

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Détails bibliographiques
Publié dans:J Invest Dermatol
Auteurs principaux: Le Saux, Olivier, Bunda, Severa, VanWart, Christopher M., Douet, Vanessa, Got, Laurence, Martin, Ludovic, Hinek, Aleksander
Format: Artigo
Langue:Inglês
Publié: 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540375/
https://ncbi.nlm.nih.gov/pubmed/16543900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.jid.5700201
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