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Inhibition of diaphanous formin signaling in vivo impairs cardiovascular development and alters smooth muscle cell phenotype

OBJECTIVE: We and others have previously shown that RhoA-dependent stimulation of myocardin related transcription factor (MRTF) nuclear localization promotes smooth muscle cell (SMC) marker gene expression. The goal of the present study was to provide direct in vivo evidence that actin polymerizatio...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Weise-Cross, Laura, Taylor, Joan M., Mack, Christopher P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540365/
https://ncbi.nlm.nih.gov/pubmed/26381868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.305879
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