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Polycomb repressive complex 1 modifies transcription of active genes

This study examines the role of Polycomb repressive complex 1 (PRC1) at active genes. The PRC1 and PRC2 complexes are crucial for epigenetic silencing during development of an organism. They are recruited to Polycomb response elements (PREs) and establish silenced domains over several kilobases. Rec...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Pherson, Michelle, Misulovin, Ziva, Gause, Maria, Mihindukulasuriya, Kathie, Swain, Amanda, Dorsett, Dale
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540264/
https://ncbi.nlm.nih.gov/pubmed/28782042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1700944
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