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Immunosuppression by CD4(+) regulatory T cells induced by chronic retroviral infection

Normal levels of CD4(+) regulatory T cells are critical for the maintenance of immunological homeostasis and the prevention of autoimmune diseases. However, we now show that the expansion of CD4(+) regulatory T cells in response to a chronic viral infection can lead to immunosuppression. Mice persis...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Iwashiro, Michihiro, Messer, Ronald J., Peterson, Karin E., Stromnes, Ingunn M., Sugie, Tomoharu, Hasenkrug, Kim J.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2001
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55402/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11459933/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.151174198
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