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Immunosuppression by CD4(+) regulatory T cells induced by chronic retroviral infection

Normal levels of CD4(+) regulatory T cells are critical for the maintenance of immunological homeostasis and the prevention of autoimmune diseases. However, we now show that the expansion of CD4(+) regulatory T cells in response to a chronic viral infection can lead to immunosuppression. Mice persis...

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Detalhes bibliográficos
Main Authors: Iwashiro, Michihiro, Messer, Ronald J., Peterson, Karin E., Stromnes, Ingunn M., Sugie, Tomoharu, Hasenkrug, Kim J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC55402/
https://ncbi.nlm.nih.gov/pubmed/11459933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.151174198
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