Discovery and characterization of a novel humanized anti-IL-15 antibody and its relevance for the treatment of refractory celiac disease and eosinophilic esophagitis

Interleukin-15 (IL-15) is a critical regulator of immune responses, especially at mucosal interfaces within the gastro-intestinal tract. Here, we describe the discovery and characterization of a humanized antibody to IL-15. Data from its epitope and mode of action, cell biology and primate pharmacol...

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Bibliografski detalji
Izdano u:MAbs
Glavni autori: Vicari, Alain P., Schoepfer, Alain M., Meresse, Bertrand, Goffin, Laurence, Léger, Olivier, Josserand, Soheila, Guégan, Nicolas, Yousefi, Shida, Straumann, Alex, Cerf-Bensussan, Nadine, Simon, Hans-Uwe, Chvatchko, Yolande
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2017
Teme:
Report
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540113/
https://ncbi.nlm.nih.gov/pubmed/28581883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2017.1332553
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