A high-throughput platform for population reformatting and mammalian expression of phage display libraries to enable functional screening as full-length IgG

Phage display antibody libraries are a rich resource for discovery of potential therapeutic antibodies. Single-chain variable fragment (scFv) libraries are the most common format due to the efficient display of scFv by phage particles and the ease by which soluble scFv antibodies can be expressed fo...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:MAbs
Autori principali: Xiao, Xiaodong, Douthwaite, Julie A., Chen, Yan, Kemp, Ben, Kidd, Sara, Percival-Alwyn, Jennifer, Smith, Alison, Goode, Kate, Swerdlow, Bonnie, Lowe, David, Wu, Herren, Dall'Acqua, William F., Chowdhury, Partha S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2017
Soggetti:
Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540111/
https://ncbi.nlm.nih.gov/pubmed/28613102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2017.1337617
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