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Tinker-OpenMM : Absolute and Relative Alchemical Free Energies using AMOEBA on GPUs

The capabilities of the polarizable force fields for alchemical free energy calculations have been limited by the high computational cost and complexity of the underlying potential energy functions. In this work, we present a GPU based general alchemical free energy simulation platform for polarizab...

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Detalhes bibliográficos
Publicado no:J Comput Chem
Main Authors: Harger, Matthew, Li, Daniel, Wang, Zhi, Dalby, Kevin, Lagardère, Louis, Piquemal, Jean-Philip, Ponder, Jay, Ren, Pengyu
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5539969/
https://ncbi.nlm.nih.gov/pubmed/28600826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcc.24853
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