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The polysialic acid mimetics idarubicin and irinotecan stimulate neuronal survival and neurite outgrowth and signal via protein kinase C

Polysialic acid (PSA) is a large, negatively charged, linear homopolymer of alpha2-8-linked sialic acid residues. It is generated by two polysialyltransferases and attached to N- and/or O-linked glycans, and its main carrier is the neural cell adhesion molecule NCAM. PSA controls the development and...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Loers, Gabriele, Astafiev, Steven, Hapiak, Yuliya, Saini, Vedangana, Mishra, Bibhudatta, Gul, Sheraz, Kaur, Gurcharan, Schachner, Melitta, Theis, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5539918/
https://ncbi.nlm.nih.gov/pubmed/28542923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14076
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