TRPV3 modulates nociceptive signaling through peripheral and supraspinal sites in rats

TRPV3 is a nonselective cation channel activated by temperatures above 33°C and is reported to be localized in keratinocytes and nervous tissue. To investigate a role for TRPV3 in pain modulation, we conducted a series of in vivo electrophysiological studies on spinal and brain nociceptive neurons....

Full description

Saved in:
Bibliographic Details
Published in:J Neurophysiol
Main Authors: McGaraughty, Steve, Chu, Katharine L., Xu, Jun, Leys, Laura, Radek, Richard J., Dart, Michael J., Gomtsyan, Arthur, Schmidt, Robert G., Kym, Philip R., Brederson, Jill-Desiree
Format: Artigo
Language:Inglês
Published: American Physiological Society 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5539442/
https://ncbi.nlm.nih.gov/pubmed/28468993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00104.2017
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items