Combining dendritic cells and B cells for presentation of oxidised tumour antigens to CD8(+) T cells

The dendritic cell (DC) is the foremost antigen-presenting cell (APC) for ex vivo expansion of tumour-specific patient T cells. Despite marked responses in some patients following reinfusion of DC-activated autologous or HLA-matched donor T cells, overall response rates remain modest in solid tumour...

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Detalhes bibliográficos
Publicado no:Clin Transl Immunology
Main Authors: Grant, Melanie L, Shields, Nicholas, Neumann, Silke, Kramer, Katrin, Bonato, Andrea, Jackson, Christopher, Baird, Margaret A, Young, Sarah L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5539416/
https://ncbi.nlm.nih.gov/pubmed/28791124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cti.2017.28
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