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Mice Immunized with IgG Anti-Sheep Red Blood Cells (SRBC) Together With SRBC Have a Suppressed Anti-SRBC Antibody Response but Generate Germinal Centers and Anti-IgG Antibodies in Response to the Passively Administered IgG

Antigen-specific IgG antibodies, passively administered together with large particulate antigens such as erythrocytes, can completely suppress the antigen-specific antibody response. The mechanism behind has been elusive. Herein, we made the surprising observation that mice immunized with IgG anti-s...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Bergström, Joakim J. E., Heyman, Birgitta
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5539184/
https://ncbi.nlm.nih.gov/pubmed/28824636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00911
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