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Bmal1 regulates inflammatory responses in macrophages by modulating enhancer RNA transcription

Bmal1 (encoded by Arntl gene) is a core circadian clock gene that regulates various genes involved in circadian rhythm. Although Bmal1 is expressed rhythmically in macrophages, the role of Bmal1 in the regulation of their cellular function remains insufficiently understood. Here, we report that Bmal...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Oishi, Yumiko, Hayashi, Shinichiro, Isagawa, Takayuki, Oshima, Motohiko, Iwama, Atsushi, Shimba, Shigeki, Okamura, Hitoshi, Manabe, Ichiro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5539165/
https://ncbi.nlm.nih.gov/pubmed/28765524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07100-3
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