Mutants of elongation factor Tu promote ribosomal frameshifting and nonsense readthrough.

This is the first report of ribosomal frameshifting promoted by mutants of the elongation factor Tu (EF-Tu). EF-Tu mutants can suppress both -1 and +1 frameshift mutations. The level of nonsense readthrough is also increased at some UGA (this paper) and UAG (Hughes, 1987) sites by these mutants. Sup...

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Publicat a:EMBO J
Autors principals: Hughes, D, Atkins, J F, Thompson, S
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1987
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC553909/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3327691/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1987.tb02772.x
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