Metabolic engineering of CHO cells for the development of a robust protein production platform

Chinese hamster ovary (CHO) cells are the most preferred mammalian host used for the bio-pharmaceutical production. A major challenge in metabolic engineering is to balance the flux of the tuned heterogonous metabolic pathway and achieve efficient metabolic response in a mammalian cellular system. P...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gupta, Sanjeev Kumar, Srivastava, Santosh K., Sharma, Ankit, Nalage, Vaibhav H. H., Salvi, Darshita, Kushwaha, Hiralal, Chitnis, Nikhil B., Shukla, Pratyoosh
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538670/
https://ncbi.nlm.nih.gov/pubmed/28763459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181455
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