The Role of S-Palmitoylation of the Human Glucocorticoid Receptor (hGR) in Mediating the Nongenomic Glucocorticoid Actions

BACKGROUND: Many rapid nongenomic glucocorticoid actions are mediated by membrane-bound glucocorticoid receptors (GRs). S-palmitoylation is a lipid post-translational modification that mediates the membrane localization of some steroid receptors. A highly homologous amino acid sequence (663YLCM KTLL...

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Publié dans:J Mol Biochem
Auteurs principaux: Nicolaides, Nicolas C., Kino, Tomoshige, Roberts, Michael L., Katsantoni, Eleni, Sertedaki, Amalia, Moutsatsou, Paraskevi, Psarra, Anna-Maria G., Chrousos, George P., Charmandari, Evangelia
Format: Artigo
Langue:Inglês
Publié: 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538142/
https://ncbi.nlm.nih.gov/pubmed/28775968
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