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Rare form of autosomal dominant familial Cornelia de Lange syndrome due to a novel duplication in SMC3

Clinical features are variable in patients with Cornelia de Lange syndrome (CdLS). Milder forms exist with structural maintenance of chromosomes 3 (SMC3) mutations. Inherited milder forms of CdLS are uncommon and may be missed if genetic testing is limited to Nipped‐B‐like protein (NIPBL) and SMC1A....

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Detalhes bibliográficos
Publicado no:Clin Case Rep
Main Authors: Infante, Elena, Alkorta‐Aranburu, Gorka, El‐Gharbawy, Areeg
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538066/
https://ncbi.nlm.nih.gov/pubmed/28781842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ccr3.1010
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