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Generation, repair and replication of guanine oxidation products
Guanine is the most readily oxidized of the four DNA bases, and guanine oxidation products cause G:C-T:A and G:C-C:G transversions through DNA replication. 8-Oxo-7,8-dihydroguanine (8-oxoG) causes G:C-T:A transversions but not G:C-C:G transversions, and is more readily oxidized than guanine. This re...
Enregistré dans:
| Publié dans: | Genes Environ |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5537945/ https://ncbi.nlm.nih.gov/pubmed/28781714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41021-017-0081-0 |
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