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Generation, repair and replication of guanine oxidation products

Guanine is the most readily oxidized of the four DNA bases, and guanine oxidation products cause G:C-T:A and G:C-C:G transversions through DNA replication. 8-Oxo-7,8-dihydroguanine (8-oxoG) causes G:C-T:A transversions but not G:C-C:G transversions, and is more readily oxidized than guanine. This re...

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Bibliografiska uppgifter
I publikationen:Genes Environ
Huvudupphovsmän: Kino, Katsuhito, Hirao-Suzuki, Masayo, Morikawa, Masayuki, Sakaga, Akane, Miyazawa, Hiroshi
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537945/
https://ncbi.nlm.nih.gov/pubmed/28781714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41021-017-0081-0
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