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Suppression of Nrf2 Activity by Chestnut Leaf Extract Increases Chemosensitivity of Breast Cancer Stem Cells to Paclitaxel

Due to metastatic potential and drug resistance, cancer stem cells (CSCs) have become a critical target for the development of chemotherapeutic agents. Recent studies showed that CSCs highly express NF-E2-related factor 2 (Nrf2)-mediated antioxidant enzymes and thereby retain relatively low levels o...

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Detalhes bibliográficos
Publicado no:Nutrients
Main Authors: Woo, Yaejin, Oh, Jisun, Kim, Jong-Sang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537874/
https://ncbi.nlm.nih.gov/pubmed/28718813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu9070760
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