Activation of V kappa gene rearrangement in pre-B cells follows the expression of membrane-bound immunoglobulin heavy chains.

During B cell development V kappa gene rearrangement seems to occur only in mu-positive pre-B cells. To study the role of the mu chain in the activation of the Ig kappa locus, we introduced expression vectors carrying different forms of the mu gene into null pre-B cells. The activation of the Ig kap...

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Библиографические подробности
Главные авторы: Reth, M, Petrac, E, Wiese, P, Lobel, L, Alt, F W
Формат: Artigo
Язык:Inglês
Опубликовано: 1987
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC553783/
https://ncbi.nlm.nih.gov/pubmed/3123216
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