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Restoration of u.v.-induced excision repair in Xeroderma D cells transfected with the denV gene of bacteriophage T4.

The heritable DNA repair defect in human Xeroderma D cells, which results in failure to incise at u.v. light-induced pyrimidine dimers, has been partially but stably corrected by transfection of immortalised cells with the denV pyrimidine dimer glycosylase gene of bacteriophage T4. Transfectants sel...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Arrand, J E, Squires, S, Bone, N M, Johnson, R T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC553753/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3319581/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1987.tb02622.x
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