Human equilibrative nucleoside transporter 1 gene expression is associated with gemcitabine efficacy in advanced leiomyosarcoma and angiosarcoma

BACKGROUND: The expression of human equilibrative nucleoside transporter 1 (hENT1), the major gemcitabine transporter into cells, has been thoroughly investigated as a predictive marker of response to gemcitabine in pancreatic cancer and biliary tract cancers. Since gemcitabine is widely used in the...

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Udgivet i:Br J Cancer
Main Authors: Vincenzi, Bruno, Stacchiotti, Silvia, Collini, Paola, Pantano, Francesco, Rabitti, Carla, Perrone, Giuseppe, Iuliani, Michele, Baldi, Alfonso, Badalamenti, Giuseppe, Sanfilippo, Roberta, Santini, Daniele, Muda, Andrea Onetti, Gronchi, Alessandro, Casali, Paolo, Dei Tos, Angelo Paolo, Tonini, Giuseppe
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Translational Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537497/
https://ncbi.nlm.nih.gov/pubmed/28641307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.187
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